On the day of treatment, your child will be infused with ZOLGENSMA.
You should give your child the second dose of the oral corticosteroid on the day of infusion as prescribed to help manage reactions to ZOLGENSMA by the body’s immune system. The actual infusion will take 60 minutes. However, ask your doctor or care team for additional details on the schedule for the day. Remember to talk to your doctor and care team about any family members you would like to have with you on treatment day. You may have the option of having your Patient Resource Manager present on the day of treatment to support your family.
Before you leave the hospital, talk with your doctor about post-treatment follow-up and additional monitoring. You will continue to give your child the corticosteroid as prescribed by your doctor. Your doctor will monitor your child’s liver function for at least 3 months after infusion through weekly clinical exams and blood tests for the first month and every other week for the second and third months. Your doctor will determine when to gradually reduce the dose of the corticosteroid and when to stop it.
- You should contact your doctor immediately if a dose of the corticosteroid is missed or vomited up
- Talk to your doctor about any side effects
In addition to liver function, your doctor will monitor other markers through blood tests, which may require weekly appointments:
- Weekly platelet counts for the first month and then every other week for the second and third months until platelet counts return to baseline
- Weekly troponin-I for the first month and then monthly for the second and third months until troponin-I level returns to baseline