SMA Atlas

Navigating life with SMA after treatment

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SMA Atlas

Navigating life with SMA after treatment

Donovan, who was diagnosed with SMA Type 1, playing with his dad Donovan, who was diagnosed with SMA Type 1, playing with his dad
SMA CARE AND MILESTONES

Building our SMA care team

Finding a trusted healthcare team is key in managing SMA. Hear from 2 caregivers and their experience building their son’s care team after diagnosis and how they’ve adapted it over time.

Daily life

A paper family holding hands

Fun for the whole family

For a child with SMA, finding activities the whole family enjoys can sometimes be challenging. Check out these caregiver-suggested fun family activities for in and out of the home.

Staying connected while staying home

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Memorable moments

Matteo, who was diagnosed with SMA Type 1, walking with his mom and dad

Matteo’s first day of school

Hear an SMA family describe the moment their son walked into class on the first day of school and why it means so much to them.

Maisie says, “Momma”

Adventures abroad with our child with SMA

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Maisie says, “Momma”
Maisie, who was diagnosed with SMA Type 1, saying, “Momma” Maisie, who was diagnosed with SMA Type 1, saying, “Momma”

SMA care and milestones

Slade, who was diagnosed with SMA Type 1, sitting with his family

Celebrating “inchstones” in SMA

Every parent looks forward to their child reaching major milestones. Hear from one family about the importance of also celebrating inchstones and what that means to them.

Building our SMA care team

Advocacy doesn’t stop after treatment

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A photo collection of Evelyn and her sister Josephine

Community and progress

A photo collection of Evelyn and her sister Josephine

SMA then and now

Hear from caregivers who lived through losing their first child because there was no SMA treatment at the time, and what having SMA treatments now means to their second child and family.

Importance of early treatment

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Important Safety Information

What is the most important information I should know about ZOLGENSMA?

  • ZOLGENSMA can cause acute serious liver injury. Liver enzymes could become elevated and may reflect acute serious liver injury in children who receive ZOLGENSMA.
  • Patients will receive an oral corticosteroid before and after infusion with ZOLGENSMA and will undergo regular blood tests to monitor liver function.

Important Safety Information

What is the most important information I should know about ZOLGENSMA?

  • ZOLGENSMA can cause acute serious liver injury. Liver enzymes could become elevated and may reflect acute serious liver injury in children who receive ZOLGENSMA.
  • Patients will receive an oral corticosteroid before and after infusion with ZOLGENSMA and will undergo regular blood tests to monitor liver function.
  • Contact the patient’s doctor immediately if the patient’s skin and/or whites of the eyes appear yellowish, or if the patient misses a dose of the corticosteroid or vomits it up.

What should I watch for before and after infusion with ZOLGENSMA?

  • Viral respiratory infections before or after ZOLGENSMA infusion can lead to more serious complications. Contact the patient’s doctor immediately if you see signs of a possible viral respiratory infection such as coughing, wheezing, sneezing, runny nose, sore throat, or fever.
  • Decreased platelet counts could occur following infusion with ZOLGENSMA. Seek immediate medical attention if a patient experiences unexpected bleeding or bruising.

What do I need to know about vaccinations and ZOLGENSMA?

  • Talk with the patient’s doctor to decide if adjustments to the vaccination schedule are needed to accommodate treatment with a corticosteroid.
  • Protection against respiratory syncytial virus (RSV) is recommended.

Do I need to take precautions with the patient’s bodily waste?

Temporarily, small amounts of ZOLGENSMA may be found in the patient’s stool. Use good hand hygiene when coming into direct contact with bodily waste for 1 month after infusion with ZOLGENSMA. Disposable diapers should be sealed in disposable trash bags and thrown out with regular trash.

What are the possible or likely side effects of ZOLGENSMA?

The most common side effects that occurred in patients treated with ZOLGENSMA were elevated liver enzymes and vomiting.

Indication

What is ZOLGENSMA?
ZOLGENSMA is a prescription gene therapy used to treat children less than 2 years old with spinal muscular atrophy (SMA). ZOLGENSMA is given as a one-time infusion into a vein. ZOLGENSMA was not evaluated in patients with advanced SMA.

The safety information provided here is not comprehensive. Talk to the patient’s doctor about any side effects that bother the patient or that don’t go away.

You are encouraged to report suspected side effects by contacting the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch, or AveXis at 833-828-3947.

Please see the Full Prescribing Information.